Pain, Muscle Cramps, Spasticity and Tremor

The most commonly reported symptom of the neurodegenerative disease Machado-Joseph Disease (MJD) is impaired mobility (experienced by 80.3% of MJD patients, Schmitz-Hubsch et al., 2010). Nevertheless, other symptoms such as pain, spasticity and tremor are also frequently reported by MJD patients and cause patients a large amount of inconvenience, discomfort and disability. This medical protocol outlines these symptoms and their prevalence, assessment and treatment.