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Research

Publications MJDF has funded and/or been involved in:

2024
Watchon M , Wright A, Ahel H , Robinson K , Plenderleith S , Kuriakose A, Yuan K and Laird A
Spermidine treatment: induction of autophagy but also apoptosis?
[2024 Mar 5] Mol Brain. 2024. 5;17(1):15. doi: 10.1186/s13041-024-01085-7.
2024
Potapenko A, Davidson J, Lee A, and Laird A
The deubiquitinase function of ataxin-3 and its role in the pathogenesis of Machado-Joseph disease and other diseases
[2024 Mar 7].Biochem J (2024) 481 (6): 461–480.
2024
Watchon M, Robinson KJ, Luu L, et al.
Treatment with sodium butyrate induces autophagy resulting in therapeutic benefits for spinocerebellar ataxia type 3
[2024 Jan 3].T he FASEB Journal. 2024; 38:e23429. doi:10.1096/fj.202300963RR
2023
Amery R, Wunungmurra JG, Raghavendra P, Bukulatjpi G, Baker R, Gumbula F et al. 
Augmentative and alternative communication for Aboriginal Australians: Developing core vocabulary for Yolŋu speakers. Augmentative and Alternative Communication
Jan 4;38(4):209-220. doi.org/10.1080/07434618.2022.2128410
2023
Gamage HKAH, Robinson KJ, Luu L, Paulsen IT, Laird AS.
Machado Joseph Disease severity is linked with gut microbiota alterations in transgenic mice
[2023 Feb 21]. Neurobiol Dis. 2023;179:106051. doi:10.1016/j.nbd.2023.106051
2022
LaGrappe D, Massey L, Kruavit A, Howarth T, Lalara G, Daniels B et al.
Sleep disorders among Aboriginal Australians with Machado-Joseph Disease: Quantitative results from a multiple methods study to assess the experience of people living with the disease and their caregivers
Neurobiology of Sleep and Circadian Rhythms. 2022 May;12:1-10. 100075. https://doi.org/10.1016/j.nbscr.2022.100075
2022
Luke J, Dalach P, Tuer L, Savarirayan R, Ferdinand A, McGaughran J, Kowal E, Massey L, Garvey G, Dawkins H, Jenkins M.
Investigating disparity in access to Australian clinical genetic health services for Aboriginal and Torres Strait Islander people
Nature Communications. Aug 24;13(1):4966
2022
Amery R, Wunungmurra JG, Bukuḻatjpi G, Dikul Baker R, Gumbula F, Yunupingu E et al. 
Designing augmentative and alternative communication systems with Aboriginal Australians: Vocabulary representation, layout, and access. Augmentative and Alternative Communication
 2022;38(4):221-235. doi.org/10.1080/07434618.2022.2129782
2021
Carr JJ, Lalara J, Lalara G, Lalara G, Daniels B, Clough AR, et al.
Staying strong toolbox: Co-design of a physical activity and lifestyle program for Aboriginal families with Machado-Joseph disease in the Top End of Australia
PLoS One. 2021 Feb 5;16 (2):1-19. e0244311. https://doi.org/10.1371/journal.pone.0244311
2021
Watchon M, Luu L, Robinson KJ, Yuan KC, De Luca A, Suddull HJ et al.
Sodium valproate increases activity of the sirtuin pathway resulting in beneficial effects for spinocerebellar ataxia-3 in vivo
Molecular Brain. 2021 Aug 20;14(1):1-16. 128. https://doi.org/10.1186/s13041-021-00839-x
2021
Robinson KJ, Yuan K, Plenderleith SK, Watchon M, Laird A.
A novel calpain inhibitor compound has protective effects on a zebrafish model of spinocerebellar ataxia type 3
Cells. 2021 Sep 29;10(10):1-15. 2592. https://doi.org/10.3390/cells10102592
2021
Robinson KJ, Tym MC, Hogan A, Watchon M, Yuan KC, Plenderleith SK, Don EK, Laird AS et al.
Flow cytometry allows rapid detection of protein aggregates in cellular and zebrafish models of spinocerebellar ataxia 3
DMM Disease Models and Mechanisms. 2021 Oct 1;14(10):1-12. dmm049023. https://doi.org/10.1242/dmm.049023
2021
Sena PP, Weber JJ, Watchon M, Robinson KJ, Wassouf Z, Hauser S et al.
Pathophysiological interplay between O-GlcNAc transferase and the Machado-Joseph disease protein ataxin-3
Proceedings of the National Academy of Sciences of the United States of America. 2021 Nov 23;118(47):1-12. e2025810118. https://doi.org/10.1073/pnas.2025810118
2021
Ferdinand A, Massey L, Cullen J, Temple J, Meiselbach K, Paradies Y et al.
Culturally competent communication in Indigenous disability assessment: a qualitative study
International Journal for Equity in Health. 2021 Dec;20(1). 68. https://doi.org/10.1186/s12939-021-01402-9
2021
Dalach P, Savarirayan R, Baynam G, McGaughran J, Kowal E, Massey L et al.
“This is my boy’s health! Talk straight to me!” perspectives on accessible and culturally safe care among Aboriginal and Torres Strait Islander patients of clinical genetics services
International Journal for Equity in Health. 2021 Dec;20(1). 103. https://doi.org/10.1186/s12939-021-01443-0
2021
Carr J.
MJD Staying Strong Toolbox – Full Video
2020
Manuneedhi Cholan P, Han A, Woodie BR, Watchon M, Kurz ARM, Laird AS et al.
Conserved anti-inflammatory effects and sensing of butyrate in zebrafish
Gut Microbes. 2020 Nov 9;12(1):1-11. e1824563. https://doi.org/10.1080/19490976.2020.1824563
2020
Robinson KJ, Watchon M, Laird AS.
Aberrant cerebellar circuitry in the spinocerebellar ataxias
Frontiers in Neuroscience. 2020 Jul 16;14:1-27. 707. https://doi.org/10.3389/fnins.2020.00707
2020
Elsum I, Massey L, McEwan C, LaGrappe D, Kowal E, Savarirayan R et al.
A community-based co-designed genetic health service model for Aboriginal Australians
PLoS One. 2020 Oct;15(10 October):1-19. e0239765. https://doi.org/10.1371/journal.pone.0239765
2019
Carr JJ, Lalara J, Lalara G, O’Hare G, Massey L, Kenny N et al.
Staying strong on the inside and outside’ to keep walking and moving around: Perspectives from Aboriginal people with Machado Joseph Disease and their families from the Groote Eylandt Archipelago, Australia
PLoS One. 2019 Mar 11;14(3):1-17. e0212953. https://doi.org/10.1371/journal.pone.0212953
2019
Ferdinand A, Massey L, Cullen J, Temple J, Chamravi D, Meiselbach K, Paradies Y, Baynam G, Savarirayan R, Kelaher M.
Understanding disability through the lens of Aboriginal and Torres Strait Islander people – challenges and opportunities
The University of Melbourne. 2019. Disability M Kelaher Report v2.docx (lowitja.org.au)
2019
Amery R, Wunungmurra JG, Gondarra J, Gumbula F, Raghavendra P, Barker R et al.
Yolŋu with Machado–Joseph disease: Exploring communication strengths and needs
International Journal of Speech-Language Pathology. 2020 Sep 2;22(5):499-510. https://doi.org/10.1080/17549507.2019.1670863
2019
Carr JJ, Lalara J, Lalara G, Lalara G, Daniels B, Clough AR et al.
What is the best way to keep walking and moving around for individuals with Machado-Joseph disease? A scoping review through the lens of Aboriginal families with Machado-Joseph disease in the Top End of Australia
BMJ Open. 2019 Sep 30;9(9):1-16. e032092. https://doi.org/10.1136/bmjopen-2019-032092
2019
Ferdinand A, Massey L, Cullen J, Temple J, Chamravi D, Meiselbach K, Paradies Y, Baynam G, Savarirayan R, Kelaher M.
Understanding disability through the lens of Aboriginal and Torres Strait Islander people – challenges and opportunities
The University of Melbourne.
2018
Acosta JR, Watchon M, Yuan KC, Fifita JA, Svahn AJ, Don EK et al.
Neuronal cell culture from transgenic zebrafish models of neurodegenerative disease
Biology Open. 2018 Oct;7(10):1-7. bio036475. https://doi.org/10.1242/bio.036475
2017
Watchon M, Yuan KC, Mackovski N, Svahn AJ, Cole NJ, Goldsbury C et al.
Calpain inhibition is protective in Machado–Joseph disease zebrafish due to induction of autophagy
Journal of Neuroscience. 2017;37(32):7782-7794.
2017
Baynam G, Molster C, Bauskis A, Kowal E, Savarirayan R, Kelaher M et al.
Indigenous genetics and rare diseases: Harmony, diversity and equity
In Advances in Experimental Medicine and Biology. Vol. 1031. Springer New York LLC. 2017. p. 511-520. (Advances in Experimental Medicine and Biology). https://doi.org/10.1007/978-3-319-67144-4_27
2017
LaGrappe D, Massey L, Couchman M, Rantell A, Rungan C.
Urinary continence and living with Machado Joseph disease: Insights from a literature review and experience of the Machado Joseph Disease Foundation
Australian & New Zealand Continence Journal. 2017;23(3):62-66.
2014
Stephens A, Cullen J, Massey L, Bohanna I.
Will the National Disability Insurance Scheme Improve the Lives of those Most in Need? Effective Service Delivery for People with Acquired Brain Injury and other Disabilities in Remote Aboriginal and Torres Strait Islander Communities
Australian Journal of Public Administration. 2014;73(2) 260–270 https://doi.org/10.1111/1467-8500.12073
2013
Massey L, Jane A, Lindop N, Christian E.
Disability Audit – NE Arnhem Land/NT Gulf – A Snapshot of Indigenous Australian Disability in the Very Remote Communities of the Groote Eylandt Archipelago (Angurugu, Umbakumba, Milyakburra), Elcho Island (Galiwin’ku), and Ngukurr (including Urapunga)
2012
Martins S, Soong BW, Wong VCN, Giunti P, Stevanin G, Ranum LPW et al.
Mutational origin of Machado-Joseph disease in the Australian aboriginal communities of Groote Eylandt and Yirrkala
Archives of Neurology. 2012;69(6):746-751. https://doi.org/10.1001/archneurol.2011.2504

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